Blended Agonist/Antagonist and Partial Agonist Opioid Analgesics The concomitant usage of opioids with other opioid analgesics, such as butorphanol, nalbuphine, pentazocine, may well lessen the analgesic effect of oxycodone and acetaminophen tablets and/or precipitate withdrawal symptoms. Recommend patient to prevent concomitant use of these drugs.